The painful shoulder is the most common condition seen in sports injury clinics. Athletes with shoulder pain who practice throwing or overhead activities frequently suffer from shoulder impingement syndrome(SIS). Rehabilitative therapies are important parts of non-operative treatment methods in these patients. To evaluate the feasibility of VR- game-based rehabilitation in athletes with SIS, a pilot study on 3 patients has been done. The participants were rehabilitated 5 times a week for 4 weeks, 20 sessions in total (with the duration of each session being 60 minutes). In addition to the conventional rehabilitation program, a 10-minute game-based virtual reality exercise was administered. The game-based virtual reality program named The clock and balls (Version 2) was used for the rehabilitation program. All three patients completed a total of 20 game-based virtual reality exercise sessions. Primary outcome measures were a range of motion evaluated with a goniometer, pain sensation, disability intensity using ‘The Disabilities of the Arm, Shoulder and Hand Questionnaire’, muscle strength using a dynamometer; pain threshold with an 'algometer', and level of satisfaction.